Search Result

Search Results for " plasminogen activator, urokinase "

Targets

Compounds

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T13408	ZK824190		Others , Serine Protease
	ZK824190 is an orally available and selective inhibitor of urokinase plasminogen activator (uPA) as a potential treatment for multiple sclerosis(IC50s of 237, 1600 and 1850 nM for uPA, tPA, and Plasmin, respectively).		Others , Serine Protease
T8362	Benzamidine hydrochloride	Benzamidine HCl	Serine/threonin kinase , Serine Protease
	Benzamidine hydrochloride (Benzamidine HCl) is a reversible inhibitor of serine proteases, including trypsin, plasmin, and thrombin (Ki of 35, 350, and 220 μM, respectively).		Serine/threonin kinase , Serine Protease
TP2338L	Cenupatide acetate	Cenupatide acetate(1006388-38-0 Free base)	Others
	Cenupatide acetate is an urokinase plasminogen activator receptor (uPAR) inhibitor for treating disorders associated altered cell migration, such as cancer.		Others
T13257	Upamostat		PAI-1 , Serine/threonin kinase , Serine Protease
	Upamostat is an inhibitor of a serine protease and is a urokinase plasminogen activator (uPA) inhibitor.		PAI-1 , Serine/threonin kinase , Serine Protease
T60248	4-Aminobenzamidine dihydrochloride	p-Aminobenzamidine dihydrochloride	Serine Protease
	4-Aminobenzamidine dihydrochloride (p-Aminobenzamidine dihydrochloride) is a strong trypsin inhibitor and a relatively weak inhibitor of urokinase type plasminogen activator (uPA) (K i =82 μM). 4-Aminobenzamidine can inh...		Serine Protease
T13251	UKI-1	UKI-1C	Others
	UKI-1 is a urokinase-type plasminogen activator system synthetic inhibitor.		Others
T13409	ZK824859		Others
	ZK824859 is an oral available and selective inhibitor of urokinase plasminogen activator (uPA)(IC50s of 79 nM, 1580 nM and 1330 nM for human uPA, tPA, and plasmin, respectively).		Others
T69751	UK-356202
	UK-356,202 is a potent and selective urokinase-type plasminogen activator (Ki = 37 nM). Urokinase plasminogen activator (uPA, urokinase) is a trypsinlike serine protease and a therapeutical target for many cancer types, ...
T70927	UCD74A HCl
	UCD74A HCl is a cell impermeant homolog of UCD38B, inhibitor of uPA (urokinase plasminogen activator).
T41085	UK122	UK122
	UK122 is a highly effective and specific inhibitor of urokinase-type plasminogen activator (uPA) with an IC50 value of 0.2 μM. It displays negligible to minimal inhibition towards tissue-type plasminogen activator (tPA),...
T13409L	ZK824859 hydrochloride (2271122-53-1 free base)	ZK824859 hydrochloride	Others
	ZK824859 hydrochloride is an oral available and selective inhibitor of urokinase plasminogen activator (uPA)(IC50s of 79 nM, 1580 nM and 1330 nM for human uPA, tPA, and plasmin, respectively).		Others
T35931	GGACK (hydrochloride)
	GGACK is an inhibitor of urokinase-type plasminogen activator (uPA) and factor Xa (Kis = 1.8 and 8.7 μM, respectively).1,2 1.Kettner, C., and Shaw, E.The susceptibility of urokinase to affinity labeling by peptides of ar...
T73701	Urokinase (peptidolytic)
	Urokinase peptidolytic (Urokinase-type plasminogen activator) is a serine protease, an inactive form (zymogen) of the serine protease plasminogen. Activation of plasmin triggers a proteolytic cascade reaction, which in t...
TP2338	Cenupatide	UPARANT,Cenupatide trifluoroacetic acid salt,Ac-Arg-Aib-Arg-α(Me)Phe-NH2)
	Cenupatide is a urokinase plasminogen activator receptor (uPAR) inhibitor. Cenupatide inhibits uPAR binding to the formyl peptide receptors (FPRs) can improve kidney lesions in a rat model of STZ-induced diabetes. Cenupa...
T78018	Plasminogen
	Plasminogen is a zymogen secreted as a precursor protein that, when cleaved by urokinase plasminogen activator (uPA) or tissue plasminogen activator (tPA), is converted into plasmin. Plasmin is a protease with broad spec...

Compounds

ZK824190

T13408

Synonym:

Target: Others, Serine Protease

Benzamidine hydrochloride

T8362

Synonym: Benzamidine HCl

Target: Serine/threonin kinase, Serine Protease

Cenupatide acetate

TP2338L

Synonym: Cenupatide acetate(1006388-38-0 Free base)

Target: PAI-1, Serine/threonin kinase, Serine Protease

4-Aminobenzamidine dihydrochloride

T60248

Synonym: p-Aminobenzamidine dihydrochloride

Target: Serine Protease

ZK824859 hydrochloride (2271122-53-1 free base)

T13409L

Synonym: ZK824859 hydrochloride

Target: Others

GGACK (hydrochloride)

T35931

Synonym:

Target:

Urokinase (peptidolytic)

Synonym: UPARANT,Cenupatide trifluoroacetic acid salt,Ac-Arg-Aib-Arg-α(Me)Phe-NH2)

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-01257	UPAR/PLAUR Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	uPAR/PLAUR Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.4 kDa and the accession number is P35456-1.
TMPY-02141	UPAR/PLAUR Protein, Human, Recombinant (His)	Human	HEK293 Cells
	uPAR/PLAUR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.8 kDa and the accession number is Q03405-1.
TMPY-00904	Urokinase/uPA Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Urokinase/uPA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46 kDa and the accession number is A0A024QZM9.
TMPY-04504	Urokinase/uPA Protein, Rat, Recombinant (His)	Rat	HEK293 Cells
	Urokinase/uPA Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 47.3 kDa and the accession number is A6KKR2.
TMPY-01017	UPAR/PLAUR Protein, Mouse, Recombinant (His & hFc)	Mouse	HEK293 Cells
	uPAR/PLAUR Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 58 kDa and the accession number is P35456-1.
TMPK-01225	MRC2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	MRC2 (Mannose Receptor C Type 2) is a constitutively recycling endocytic receptor belonging to the mannose receptor family, which has been found to be closely involved with cancer metastasis. MRC2 expresses an extracellu...
TMPK-00782	PLAU/uPA Protein, Mouse, Recombinant (His & Avi)	Mouse	HEK293 Cells
	Plasminogen activator, urokinase (uPA) is a secreted serine protease whose Dysregulation is often accompanied by various cancers. PLAU inhibition could suppress tumor growth. Collectively, PLAU is necessary for tumor pro...
TMPY-01711	Serpin B2 Protein, Human, Recombinant (GST)	Human	Baculovirus Insect Cells
	Serpins are the largest and most diverse family of serine protease inhibitors which are involved in some fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesis, infl...
TMPJ-00625	Serpin E1 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Plasminogen activator inhibitor-1 (serpin E1) is a serine protease inhibitor which belongs to the serpin family. Serpin E1 acts as 'bait' for tissue plasminogen activator, urokinase, protein C and matriptase-3/TMPRSS7. I...
TMPH-01869	PAI-2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Inhibits urokinase-type plasminogen activator. The monocyte derived PAI-2 is distinct from the endothelial cell-derived PAI-1. PAI-2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with N-10xHis ...
TMPH-03397	UPAR/PLAUR Protein, Rat, Recombinant (His)	Rat	E. coli
	Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. uPAR/PLAUR Protein,...
TMPH-01508	HABP2 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Cleaves the alpha-chain at multiple sites and the beta-chain between 'Lys-53' and 'Lys-54' but not the gamma-chain of fibrinogen and therefore does not initiate the formation of the fibrin clot and does not cause the fib...
TMPK-00216	UPAR/PLAUR Protein, Mouse, Recombinant (His & Avi), Biotinylated	Mouse	HEK293 Cells
	The receptor (u-PAR) for urokinase plasminogen activator (u-PA) is a three-domain protein, GPI-anchored to the cell surface, which focuses the enzymatic activity of u-PA, and allows the cell surface activation of plasmin...
TMPK-00539	PLAU/uPA Protein (active form), Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	Plasminogen activator, urokinase (uPA) is a secreted serine protease whose Dysregulation is often accompanied by various cancers. PLAU inhibition could suppress tumor growth. Collectively, PLAU is necessary for tumor pro...
TMPK-00783	PLAU/uPA Protein, Mouse, Recombinant (His & Avi), Biotinylated	Mouse	HEK293 Cells
	Plasminogen activator, urokinase (uPA) is a secreted serine protease whose Dysregulation is often accompanied by various cancers. PLAU inhibition could suppress tumor growth. Collectively, PLAU is necessary for tumor pro...
TMPK-00274	PLAU/uPA Protein (active form), Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	Plasminogen activator, urokinase (uPA) is a secreted serine protease whose Dysregulation is often accompanied by various cancers. PLAU inhibition could suppress tumor growth. Collectively, PLAU is necessary for tumor pro...
TMPK-01175	UPAR/PLAUR Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	The receptor (u-PAR) for urokinase plasminogen activator (u-PA) is a three-domain protein, GPI-anchored to the cell surface, which focuses the enzymatic activity of u-PA, and allows the cell surface activation of plasmin...
TMPK-00226	UPAR/PLAUR Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	The receptor (u-PAR) for urokinase plasminogen activator (u-PA) is a three-domain protein, GPI-anchored to the cell surface, which focuses the enzymatic activity of u-PA, and allows the cell surface activation of plasmin...
TMPK-00215	UPAR/PLAUR isoform 1 Protein, Mouse, Recombinant (His & Avi)	Mouse	HEK293 Cells
	The receptor (u-PAR) for urokinase plasminogen activator (u-PA) is a three-domain protein, GPI-anchored to the cell surface, which focuses the enzymatic activity of u-PA, and allows the cell surface activation of plasmin...
TMPK-00228	UPAR/PLAUR Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	The receptor (u-PAR) for urokinase plasminogen activator (u-PA) is a three-domain protein, GPI-anchored to the cell surface, which focuses the enzymatic activity of u-PA, and allows the cell surface activation of plasmin...
TMPK-00227	UPAR/PLAUR Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	The receptor (u-PAR) for urokinase plasminogen activator (u-PA) is a three-domain protein, GPI-anchored to the cell surface, which focuses the enzymatic activity of u-PA, and allows the cell surface activation of plasmin...
TMPH-02834	PAI-1 Protein, Mouse, Recombinant (His & SUMO)	Mouse	E. coli
	Serine protease inhibitor. Inhibits TMPRSS7. Is a primary inhibitor of tissue-type plasminogen activator (PLAT) and urokinase-type plasminogen activator (PLAU). As PLAT inhibitor, it is required for fibrinolysis down-reg...
TMPH-02922	SRPX2 Protein, Mouse, Recombinant (His & Myc)	Mouse	Baculovirus Insect Cells
	Acts as a ligand for the urokinase plasminogen activator surface receptor. Plays a role in angiogenesis by inducing endothelial cell migration and the formation of vascular network (cords). Involved in cellular migration...
TMPH-02923	SRPX2 Protein, Mouse, Recombinant (His & Myc & SUMO)	Mouse	E. coli
	Acts as a ligand for the urokinase plasminogen activator surface receptor. Plays a role in angiogenesis by inducing endothelial cell migration and the formation of vascular network (cords). Involved in cellular migration...
TMPY-01718	Serpin B12 Protein, Mouse, Recombinant (His)	Mouse	Baculovirus Insect Cells
	Serpins are the largest and most diverse family of serine protease inhibitors which are involved in some fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesis, infl...
TMPJ-01282	Serpin B12 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Serpin B12 is a member of the serpin family. Serpins are the largest and most diverse family of serine protease inhibitors. Most serpins are secreted and attain physiologic concentrations in the blood and extracellular f...
TMPJ-01320	BSSP-4 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Brain-Specific Serine Protease 4 (BSSP-4) is a serine protease that preferentially cleaves the synthetic substrate H-D-Leu-Thr-Arg-pNA compared to tosyl-Gly-Pro-Arg-pNA. BSSP-4 is expressed abundantly in the epithelial c...